Childhood sarcoidosis presenting with extensive cutaneous lesions, bilateral hilar lymphadenopathy and severe hypercalcaemia
Identifieur interne : 001B74 ( Main/Exploration ); précédent : 001B73; suivant : 001B75Childhood sarcoidosis presenting with extensive cutaneous lesions, bilateral hilar lymphadenopathy and severe hypercalcaemia
Auteurs : Neil J. Mortimer [Royaume-Uni] ; Michael J. Sladden [Royaume-Uni] ; Sarah E. Hill [Nouvelle-Zélande] ; Robin Ac Graham-Brown [Royaume-Uni]Source :
- Australasian Journal of Dermatology [ 0004-8380 ] ; 2007-11.
English descriptors
- Teeft :
- Atopic dermatitis, Australasian, Australasian college, Authors journal compilation, Calcium metabolism, Childhood sarcoidosis, Complete resolution, Cutaneous, Cutaneous lesions, Dermatologist, Epithelioid granulomata, Granuloma, Hilar lymphadenopathy, Hypercalcaemia, Lesser extent, Lymph node biopsies, Lymphadenopathy, Mediastinal lymphadenopathy, Node, Papule, Perioral distribution, Prednisolone, Right paratracheal adenopathy, Sarcoidosis, Serum calcium, Severe hypercalcaemia, Young children.
Abstract
A 9‐year‐old boy with a history of atopic dermatitis presented with a 4‐month history of an asymptomatic papular eruption. This was predominantly perioral in distribution with lesser involvement of the neck, arms and trunk. Investigations revealed severe hypercalcaemia of 3.77 mmol/L (normal range 2.10–2.60) and bilateral hilar lymphadenopathy. The diagnosis of sarcoidosis was supported by granulomata in skin and lymph node biopsies on histopathological examination. Prednisolone (2 mg/kg/day) rapidly normalized serum calcium.
Url:
DOI: 10.1111/j.1440-0960.2007.00393.x
Affiliations:
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Hill</name></author><author><name sortKey="Graham Rown, Robin Ac" sort="Graham Rown, Robin Ac" uniqKey="Graham Rown R" first="Robin Ac" last="Graham-Brown">Robin Ac Graham-Brown</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:0786217AA78FBBB6D7B2CA0133D1ECFDEC3EA9D3</idno><date when="2007" year="2007">2007</date><idno type="doi">10.1111/j.1440-0960.2007.00393.x</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-K8TNKLRP-X/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001075</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001075</idno><idno type="wicri:Area/Istex/Curation">001075</idno><idno type="wicri:Area/Istex/Checkpoint">000A57</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000A57</idno><idno type="wicri:doubleKey">0004-8380:2007:Mortimer N:childhood:sarcoidosis:presenting</idno><idno type="wicri:Area/Main/Merge">001B85</idno><idno type="wicri:Area/Main/Curation">001B74</idno><idno type="wicri:Area/Main/Exploration">001B74</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Childhood sarcoidosis presenting with extensive cutaneous lesions, bilateral hilar lymphadenopathy and severe hypercalcaemia</title><author><name sortKey="Mortimer, Neil J" sort="Mortimer, Neil J" uniqKey="Mortimer N" first="Neil J" last="Mortimer">Neil J. 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Hill</name><affiliation wicri:level="1"><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Department of Dermatology, Waikato Hospital, Hamilton</wicri:regionArea><wicri:noRegion>Hamilton</wicri:noRegion></affiliation></author><author><name sortKey="Graham Rown, Robin Ac" sort="Graham Rown, Robin Ac" uniqKey="Graham Rown R" first="Robin Ac" last="Graham-Brown">Robin Ac Graham-Brown</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Dermatology, Leicester Royal Infirmary, Leicester</wicri:regionArea><wicri:noRegion>Leicester</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Australasian Journal of Dermatology</title><title level="j" type="alt">AUSTRALASIAN JOURNAL DERMATOLOGY</title><idno type="ISSN">0004-8380</idno><idno type="eISSN">1440-0960</idno><imprint><biblScope unit="vol">48</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="233">233</biblScope><biblScope unit="page" to="235">235</biblScope><biblScope unit="page-count">3</biblScope><publisher>Blackwell Publishing Asia</publisher><pubPlace>Melbourne, Australia</pubPlace><date type="published" when="2007-11">2007-11</date></imprint><idno type="ISSN">0004-8380</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0004-8380</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Atopic dermatitis</term><term>Australasian</term><term>Australasian college</term><term>Authors journal compilation</term><term>Calcium metabolism</term><term>Childhood sarcoidosis</term><term>Complete resolution</term><term>Cutaneous</term><term>Cutaneous lesions</term><term>Dermatologist</term><term>Epithelioid granulomata</term><term>Granuloma</term><term>Hilar lymphadenopathy</term><term>Hypercalcaemia</term><term>Lesser extent</term><term>Lymph node biopsies</term><term>Lymphadenopathy</term><term>Mediastinal lymphadenopathy</term><term>Node</term><term>Papule</term><term>Perioral distribution</term><term>Prednisolone</term><term>Right paratracheal adenopathy</term><term>Sarcoidosis</term><term>Serum calcium</term><term>Severe hypercalcaemia</term><term>Young children</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A 9‐year‐old boy with a history of atopic dermatitis presented with a 4‐month history of an asymptomatic papular eruption. This was predominantly perioral in distribution with lesser involvement of the neck, arms and trunk. Investigations revealed severe hypercalcaemia of 3.77 mmol/L (normal range 2.10–2.60) and bilateral hilar lymphadenopathy. The diagnosis of sarcoidosis was supported by granulomata in skin and lymph node biopsies on histopathological examination. Prednisolone (2 mg/kg/day) rapidly normalized serum calcium.</div></front></TEI><affiliations><list><country><li>Nouvelle-Zélande</li><li>Royaume-Uni</li></country></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Mortimer, Neil J" sort="Mortimer, Neil J" uniqKey="Mortimer N" first="Neil J" last="Mortimer">Neil J. Mortimer</name></noRegion><name sortKey="Graham Rown, Robin Ac" sort="Graham Rown, Robin Ac" uniqKey="Graham Rown R" first="Robin Ac" last="Graham-Brown">Robin Ac Graham-Brown</name><name sortKey="Sladden, Michael J" sort="Sladden, Michael J" uniqKey="Sladden M" first="Michael J" last="Sladden">Michael J. Sladden</name></country><country name="Nouvelle-Zélande"><noRegion><name sortKey="Hill, Sarah E" sort="Hill, Sarah E" uniqKey="Hill S" first="Sarah E" last="Hill">Sarah E. Hill</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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